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Yet despite these positive developments, it is easy to feel frustrated by the visible failures of evidence to influence policy in so many areas.
The spectacular failures of "evidence based" medical theories include the millions spent on ineffective AIDS vaccines, the collapse of interferon as the wonder drug for cancer, and the marginal decrease in cancer deaths despite billions wasted during decades of fruitless research.
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Many factors contribute to this gap in healthcare for consumers with LBP, including the failure of evidence to be translated into best practice [ 5- 7], an inadequately trained and skilled health workforce [ 8, 9] and a lack of co-ordinated interdisciplinary care [ 10], the latter being a favoured model for consumers with persistent LBP [ 11].
Of the 9 patients who were considered to have obtained clinical cure by the investigator but required a second procedure, the surgical review panel changed 2 patients' outcomes (1 per treatment arm) from cure to failure because of evidence of ongoing infection at the time of the second intervention.
Clinical and/or radiological deterioration in the 2 months after the end of radiotherapy should be interpreted with caution and not automatically be considered as a treatment failure (standard, level of evidence: C).
Despite the overall failures of the reign, evidence from his charters and coinage suggest that Ethelred's government was more effective than was once believed.
Recovery of disease is made the standard of treatment, and all failures are evidence of malpractice!
13 AHFS hospitalisation was a priori defined as a new onset or worsening of signs and symptoms of heart failure with evidence of fluid overload requiring at least 24 h overnight hospitalisation and the use of intravenous diuretics.
Event-free survival (EFS) was calculated from the date of diagnosis to the date of treatment failure, relapse, evidence of disease progression or death due to any cause.
To embrace failures as evidence of being a real person (who did have a piece of pie last night).
For dependent ankle edema only (ie, no clinical signs of heart failure) due to lack of evidence and compression hosiery usually more appropriate.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com