Failure to undergo FGM renders you unmarriable because you are seen as a child, no matter your age.
After excluding 363 women due to missing information from the electronic health record or failure to undergo their scheduled ablation, 5936 women were eligible for analysis.
Thus, failure to undergo apoptosis in response to anticancer therapy because of defects in death receptor pathways may result in resistance.
In females, there is often failure to undergo final oocyte maturation, ovulation and spawning; while in males milt production may be reduced and of low quality.
They formulate the "cautionary tale" that "at least in the case of folkbiology, standard populations may be nonstandard and vice versa" (p. 114), and cognitive processes considered as normal might be actually the "failure to undergo 'normal' perceptual development" (p. 110).
The particular molting defect seen with apl-1 RNAi is indicative of a failure to undergo ecdysis, or shedding of the old exoskeleton [38].
A striking characteristic of RB-deficient cells in response to CDDP is their failure to undergo a senescent-like cell cycle arrest.
Moreover, alternative mechanisms of refractoriness could arise from increased DDR, failure to undergo DDR and/or inoperative communication between DDR and apoptosis [46] [47].
In vitro exposure of patient samples to etoposide, a DNA damaging agent, revealed three distinct "DNA damage response (DDR /apoptosis" profiles: 1) AML blasts with a defective DDR and failure to undergo apoptosis; 2) AML blasts with proficient DDR and failure to undergo apoptosis; 3) AML blasts with proficiency in both DDR and apoptosis pathways.
Three distinct responses exemplified by the 2D flow plots in Figure 4A were observed: (1) AML blasts with a defective DDR and failure to undergo apoptosis (2) AML blasts with proficient DDR and failure to undergo apoptosis (3) AML blasts with proficiency in both DDR and apoptosis (Figure 4A).
Whereas it was shown that high DNA fragmentation, and likely apoptosis, is a feature of various epithelia in CF it is now admitted that failure to undergo apoptosis could contribute to the pathogenesis of the disease [32] [35].
