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HFM is characterized by an onset of macrocytic folate-deficiency, anemia, and failure to thrive within the first months of life.
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A complete knockout of ADAM23 in mice results in ataxia, tonic-clonic seizures, failure to thrive and death within two weeks from birth [ 23, 24].
To more fully understand the growth-restricted phenotype, we examined body composition at two time points, within the failure to thrive phase and after catch-up growth had occurred (Fig. 3d).
Patients generally present within days or months of birth with symptoms of failure to thrive, poor feeding, and vomiting.
Dr. Rosenbaum's grandmother's diagnosis was "failure to thrive".
A 19-Month-Old Girl with Failure to Thrive.
Infants died of "convulsions," "fits" or "failure to thrive".
The disorder is characterized by life-threatening ketoacidosis, lethargy, failure to thrive, and developmental delay.
Thus, FE1 is performed as work-up for children with failure to thrive (FTT).
Failure to thrive (FTT) is a feature of children with Potocki-Lupski syndrome (PTLS) [duplication 17p11.2].
PTLS is characterized by hypotonia, failure to thrive, reduced body weight, intellectual disability, and autistic features.
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