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Whether the biochemical abnormalities that lead to the disordered growth and differentiation of a malignant tumour affect cell surface receptors, membrane or cytoplasmic signalling proteins or nuclear transcription factors, the end result is the inappropriate expression of some genes and failure to express others.
The cells were validated as MSCs by expression of CD105, CD73, CD90 and CD44, and failure to express CD34, HLA- DR, CD45, CD14 and CD19.
The failure to express many recombinant proteins in a soluble, physiologically active form in heterologous expression hosts indirectly evidences also the potential effect of the translation attenuation on protein biogenesis.
Activists cited their leaders' failure to express a vision for the country in plain language and to address detailed policy issues in a way voters wanted.
In one of the low points on that sporadically feminist show, Riley cheats on Buffy, and then his infidelity is blamed on Buffy, whose strength and failure to express neediness makes Riley feel inadequate.
For, while it may readily be admitted that a building can express many other things besides its function and structure, failure to express the latter in some manner, however remote, must always lead to arbitrariness.
Mr. Kidwa said the Palestinian leadership had never complained to the secretary general directly about his condemnations of suicide bombings but had conveyed its concerns over the Secretariat's failure to express "similar outrage to Israeli military assaults against the Palestinian civilian population".
The foreigners' failure to protect Baghdad's hospitals, rare books and priceless antiquities, while keeping the empty Ministry of Petroleum under tight guard, is widely read as a sign of malign intent.The failure to express a clear vision or timetable for America's role add to suspicions.
In monocytes from CRMO patients, impaired ERK1/2 signaling results in failure to express IL-10 and IL-19.
In particular, failure to express one's own anger is related to more intense and frequent pain [5, 6, 8].
Individuals who hold anger-in experience an increased pain severity, failure to express anger leads to more disability[4, 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com