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Recessively inherited defects in several COX assembly proteins result in the failure to assemble a functional holoenzyme and underlie a number of mitochondrial respiratory chain disease presentations characterised by isolated COX deficiency.
It includes, for example, errors in transcribing numbers, errors in arithmetic, and the failure to assemble all the documents in a record.
arl-8 mutants prematurely accumulate presynaptic cargoes within the proximal axon of several neuronal classes, with a corresponding failure to assemble presynapses distally.
It doesn't take a Ph.D. in government to recognize that the real subject for discussion should be the government's chronic failure to assemble, review and act on information about potential terrorist plots.
Mr. Byrd said his warnings about the failure to assemble an international coalition before the war had proved true, as American lives are lost in the postwar period and as allies continue to be reluctant to volunteer large numbers of troops to replace battle-weary Americans.
Ben Ginsberg, the chief counsel for the Romney campaign, said during the call that Mr. Santorum's failure to assemble a full slate of delegates in Ohio — as well as his failure to get on the ballot at all in some other Super Tuesday states — "should give Republican voters great pause as we get ready to face President Obama".
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Although effects on transcription have not been ruled out, the simplest model is that the failure to properly assemble the snoRNP/snRNPs leads to their accelerated degradation by a yet-to-be-determined degradation pathway.
These data suggest that the 40S pre-ribosome nuclear export defect observed in slx9∆ and slx9-1 cells is due to their failure to efficiently assemble Crm1-export complexes on 40S pre-ribosomal particles.
The failure of r ts107 202 to assemble virion particles in 293 cells at 39 degrees furthermore suggests that virus assembly is dependent upon cellular factors that differ in HeLa and 293 cell.
This leads to exaggerated IL-1β production as a result of failure to remove assembled NLRP3 complexes.
There is no clear data that sheds light on how this lower occupancy or failure to re-assemble nucleosomes might inhibit PolII.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com