Thus, the failure of wild-type mice to show an increase in incidence of leukemogenesis at low doses of genotoxic carcinogens may be due not to a statistical rarity, but to various p53-related pharmacophysiological functions, possibly including DNA repair and apoptosis that may account for a threshold.
The failure of wild-type MuHV-4 to do the same argues that gp150 is normally engaged only down-stream of gp70 or gH/gL.
This is different from the complete failure of wild-type FBM neurons to migrate in vangl2 or scrib mutant hosts (Jessen et al., 2002; Wada et al., 2005), consistent with a non-cell-autonomous role for these PCP proteins in polarizing the environment.
Absence of ononitol in wild-type HPLC chromatograms and failure of the wild-type protein extracts to produce ononitol, together with the Western analysis results suggest possible absence of native IMT-like activity in B. napus.
With Ann, she wonders whether promiscuity comes not from being a moral failure but "a sort of wild thing of trying to communicate".
Failure of sufficient amplification in wild samples may be due to mutations in primer binding regions.
Because of recent problems with persistence of wild polioviruses, vaccine failure has been restudied in Nigeria and India (77, 82).
19 These and other mutations are associated with a significantly higher risk of virological failure than wild type genotypes.
Infections occurring in the presence of MIV-150 (observed after daily MIV-150 or every other day MIV-150/zinc acetate treatment) might reflect the selection of drug resistant variants or simply failure of the drug to prevent wild type virus infection.
Interestingly, the angle of failure in the wild type group (128%) was comparable to the hTNFtg + TNFi group (98%), but significantly increased in the hTNFtg group (221%, wild type vs. hTNFtg: p = 0.0293; hTNFtg vs. hTNFtg + TNFi: p = 0.014).
