Sentence examples for failure of uptake from inspiring English sources

The uptake was scored as good when complete and dense uptake occurred throughout the tumor, fair when inhomogeneous uptake occurred throughout the tumor, and poor when there was evidence of failure of uptake.

First, how does the host recognize, take up, and maintain appropriate symbionts without generating a deleterious immune response that could result in a failure of algal uptake, digestion of the algae after uptake, or apoptosis of the host cells?

Figures 1 and 2 show the potential benefit of including FDG-PET in radiotherapy planning for LAPC. Figure 3 illustrates one of the potential limitations of FDG-PET in LAPC, namely the failure of FDG uptake to differentiate between tumour glucose metabolism and uptake in inflammatory cells.

The increased TB concentration might be attributed to the failure of normal uptake, conjugation and excretion by the damaged hepatic parenchyma [30].

There are numerous reasons why drugs may be ineffective, but the most obvious one is a failure of its uptake into the infected host cell.

Moreover, loss or attenuation of reactive astrocyte functions might worsen outcome after various kinds of CNS insults, e.g. through excitotoxic failure of glutamate uptake [46], [47] or increased inflammation or infection due to loss of astrocyte barrier functions [46], [48], [49].

The development of multidrug resistance is also associated with the failure of drug uptake.

In the host environment, the success or failure of Fe uptake processes impacts the outcome of pathogenesis [ 11].

The link between 3-MGC aciduria and mitochondrial dysfunction may involve failure of mitochondrial uptake of 3-MGC acid or potentially defective ubiquinone biosynthesis leading to increased levels of mevalonate in the mevalonate shunt pathway with subsequent increased synthesis of 3-MGC acid [ 27].

While we were preparing this manuscript, Nakase et al. have independently identified SPBC18H10.20c as a gene whose mutation suppressed a growth defect of tsc2Δ caused by a failure of leucine uptake and referred to this gene product as Any1 (Nakase et al., 2013; see Discussion).

We identified arn1+ as a gene whose high-copy expression confers canavanine resistance on wild-type cells using a S. pombe genomic library (Fig. 1), whereas any1+ was isolated in a screening for mutations that restore a growth defect of tsc2Δ owing to a failure of leucine uptake (Nakase et al., 2013).