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Therefore, it might be the SRP treatment itself that causes a failure of treating periodontal inflammations during pregnancy as well as preventing adverse birth outcomes.
At present, the high rate of recurrence and metastasis of postoperative non-small cell lung cancer (NSCLC) patients is one of the leading causes resulting in failure of treating lung cancer.
This may be one of the reasons that explain the frequent failure of treating CoNS infections with conventional antibiotics in patients with foreign body infections when the devices are not removed.
Two years after the first European study by Shortt et al. [ 24] that followed the institution of GMP regulations, Kolli et al. [ 39] (Royal Victoria Infirmary-Newcastle UNewcastle, Newcastle Upon Tyne, United Kingdom) attempted to attribute the success or failure of treating LSCD with CLET solely to the cell product.
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The primary efficacy endpoint was the composite efficacy failure rate of treated biopsy-proven acute rejection (tBPAR), graft loss or death at 12 months posttransplantation (excluding events before randomization).
Reasons are multifactorial, including patient reluctance or inability to access healthcare services (Schwarcz et al, 1997), and failure of a treating clinician to identify the need for prophylaxis (Auperin et al, 1994).
Of these patients, 113 completed the study and 20 prematurely withdrew from the study because of failure to treat one episode of migraine (n = 9), lost to follow-up (n = 4), withdrawal of consent (n = 3), dissatisfaction to assigned treatment (n = 1), occurrence of an adverse event (n = 1), protocol violation (n = 1), lack of cooperation (n = 1).
It is possible that valid reasons existed for some or all of these episodes of "failure to treat," but that this rationale was not documented and therefore not apparent to the investigators.
This raises the possibility that failure to eradicate ovarian cancers may be because of failure to treat the definitive target: cancer stem-like cells.
Clearly, the diagnosis of PG should raise the possibility of concomitant AIH, since its diagnosis can be challenging and the results of failure to treat it devastating.
18 29 We chose the outcomes of admission for oesophagitis, gastro-oesophageal reflux disease, and aspiration pneumonia as a complication of failure to treat gastro-oesophageal reflux disease.
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