After failure of stage I treatment (with benzodiazepines) and failure of stage II treatment (with phenytoin, levetiracetam, or valproic acid), 31 43 % of patients enter the refractory stage [ 118, 119].
Hence, the authors attributed the low OS rate of patients with stage IIb NPC in the radiotherapy alone group to distant metastasis, the main reason of treatment failure of stage IIb NPC.
So when he agreed to share his story of failure on stage, I was moved.
He finds that having foreseen the catastrophe does not make it any easier to bear; it is as painful as the unexpected shock of his failure on stage.
In conclusion, the prevalent chromosome instability in all early human cleavage stage embryos (post-IVF/ICSI) provides a biological basis for the failure of cleavage stage PGS in improving the live birth rate per embryo transferred.
(3, 4) The failure of TNM staging to serve as a reliable prognostic system for patients with intermediate-stage tumors may be overcome by considering morphologic, molecular, or treatment-related factors that can stratify patients more precisely into different categories of risk.
Whereas Dabney and Storey attribute the non-uniform p-values to violations of the Stage II model assumptions, we provide evidence that the non-uniformity can be attributed to the failure of the Stage I analyses to correct for systematic biases in the raw data matrix.
A perspective is provided on the failure of late-stage clinical trials across a range of platforms focusing particularly on melanoma and prostate cancer.
On this basis, the tip of the tongue phenomenon may readily be explained as arising from a successful episode of retrieval from storage, followed by a failure of the stage of translation into natural language.
Polymicrobial infection is traditionally considered a risk factor for failure of one-stage revision in the management of PJI presenting a contraindication for this type of surgery [19, 28].
