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Emergency colorectal cancer resection has been identified as "the clearest evidence on an individual level for a failure of screening" [ 54].
7 No direct observation of the disease in the detectable preclinical phase is available, even in principle, and therefore the estimate was based on the failure of screening.
As a significant number of cases present with metastatic disease when the primary tumor is not locally advanced [ 6], one can hypothesize that there is heterogeneity in tumor biology between patients, versus a failure of screening.
Of the many quality indicators identified, only ADR has been shown to independently predict CRC diagnosis after colonoscopy, an important public health outcome that suggests failure of screening [ 11].
In the '02 19' × 'Sachinoka' and 'Kaorino' × 'Akihime' populations, polymorphic marker screening was only performed with parental lines that caused failure of screening
There is much discussion in the literature on the failure of screening approaches to deliver novel antibacterial lead series, and linkage of this poor success rate for antibacterials with the chemical space properties of screening collections.
Similar(52)
All primers were obtained (from Eurofins MWG, Ebersberg, Germany) and matched regions with an identical nucleic acid sequence in compared genomes and DNA sequences of the genus Francisella to minimize amplification failure of screened isolates.
Our finding of a lack of consensus on the need for universal screening of apparently healthy individuals is consistent with the failure of FASD screening to meet some of these requirements.
Given the failure of mass screening to identify this group, we are at present in the position of trying to identify early symptomatic disease.
As noted by the US Centers for Disease Control and Prevention CDCC), previous testing of source material was inadequate due to the routine failure of serologic screening to detect newly infected donors in the pre-seroconversion phase of infection.
2 This is a careful suggestion to save lives and is based on both the therapeutic nature of total gastrectomy in >90% of mutation carriers, and the low sensitivity and failure of current screening, including endoscopy, positron emission tomographic scanning, or chromoendoscopy-directed biopsies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com