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Mechanistically, it appears that the failure of propagation through the network is the result of the increased conductance during UP states.
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Chronic MI caused frequent failure of AP propagation into subcellular regions which underwent t-tubule remodelling, producing local 'SDs'SDs
Those studies independently proposed various hypotheses for the mechanism of this depression including exocytosis-driven inhibition, failure of AP propagation, and inactivation of VGCCs.
With faster pacing rates, transmural heterogeneity was intensified, eventually causing failure of electrical propagation (conduction block) in the ischaemic core, re-entry via the border zone, and VT.
In contrast, high-frequency fatigue was attributed to failure of impulse propagation across the sarcolemma; force declines rapidly under these conditions and recovers within seconds to minutes after the end of contractions.
The model integrates the notions of QoS, GoS, failures and failure propagation between the physical and the logical level as well as circuit routing.
Failure of action potential propagation into the distal dendrites often occurs at branch points.
Bradyarrhythmia is a common heart rhythm abnormality comprising number of diseases and is associated with decreased heart rate due to the failure of action potential generation and propagation at the sinus node.
Before we discuss in detail the loss of wave-pinning at low molecule numbers, we revisit the phenomenon of propagation failure.
Indeed, as before, when the grid becomes rougher, secondary effects of propagation failure manifest themselves and affect the pinning positions through this independent mechanism.
Percentage of load loss reveals transmission capacity of the whole power grid, which is used to measure the breadth of failure propagation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com