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This is due to the smaller percentage of land area in the Kyushu District within the studied region and to the failure of penetration of these blocks by LoS with a variety of azimuths.
(2004) showed a failure of penetration of excitation when one end received high glucose and other end was not excited sufficiently; this suggested that gap junctions may not be efficient at inducing synchrony throughout the islet.
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Failure of Aβ penetration into the tissue cannot explain the differences between single cells and the more complex brain tissue.
Participation of the efflux pumps of the resistance-nodulation-cell division (RND) family was involved in the development of CAM resistance in H. pylori biofilm and failure of CAM penetration into the biofilm interior due to the presence of the extracellular matrix was also demonstrated.
Another source of failure: the high penetration of personal computers in the U.S. Says Streeter: "By the time the Minitel was introduced in the U.S., it was old and tired-looking compared to the PC market".
We have verified that ovarian cancer cell penetration of this synthetic matrix is independent of MMPs as evidenced by a failure of GM6001 to block cell penetration (data not shown).
The resulting knockout is almost never 100% complete as in some cells recombination will not be induced due to issues such as low ligand (tamoxifen) penetration or failure of the ligand to induce recombination.
While the reasons for the clinical failure of tarenflurbil are unknown, low penetration across the blood brain barrier (BBB) and, consequently, insufficient target engagement in the brain may be likely explanations [ 21].
Knockout mice generated in this manner are almost never 100% complete as in some cells recombination will not be induced due to issues such as low ligand (Tamoxifen) penetration or failure of the ligand to induce recombination, thus explaining the small focal area of epithelial staining.
We believe that the knockout model recombining a floxed Arid1a with CRE-ERT2 is not 100% complete as in some cells recombination will not be induced due to issues such as low ligand (tamoxifen) penetration or failure of the ligand to induce recombination.
One commonly cited rationalization of the failure of antibacterial drug discovery projects is lack of penetration to the site of action of the drugs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com