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All this is duly reported in "A Writer's Life," which as Mr. Talese admitted, is in part a record of failure, of leads that don't quite pan out.
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8. C.M. Christensen and J.L. Bower, "Customer Power, Strategic Investment, and the Failure of Leading Firms," Strategic Management Journal 17, no. 3 (March 1996): 197-218.
In truth, the failure of Lead... or Leave was a case of too much, too soon.
Failure of ICD leads is a major issue and has been highlighted by the Fidelis lead recall.
Alternatively, failure of protection leads to epithelial damage damage that when progressive translates into symptoms (heartburn) and signs of GERD.
Failure of autophagy leads to accumulation of cargo and autophagy substrates such as p62/SQSTM1, NBR1 and tau.
In the cerebrum, loss of brain tissue and failure of development leads to the formation of cavitating lesions, i.e. hydranencephaly and porencephaly [ 10].
Failure of this leads to increased protein kinase C activity and it has been postulated that this is responsible for the development of a TMA (Quaggin, 2013).
It is suggested that failure of proteolysis leads to accumulation of damaged proteins, increased cellular stress and increased interferon (IFN) signalling.
In the US, the failure of universities led eventually to federal government intervention.
This failure of compliance led to an eruption of dozens of new cases.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com