Sentence examples for failure of efficacy from inspiring English sources

The reason for this apparent failure of efficacy is unclear and may reflect intrinsic properties of the inhibitor employed.

Even with large samples, there can be controversy about the interpretation of the evidence, as shown by the data on the relationship between CYP2C19 variants and failure of antiplatelet efficacy of clopidogrel.

We can only speculate about the failure of self-efficacy to predict adherence in the maintenance phase of LIFE-P.

Their large size causes poor blood brain barrier penetration [7], and high antigenicity may lead to failure of long term efficacy.

By local pathology and central reading, the rates of efficacy failure were equivalent between the groups.

Novel circulatory biomarkers could improve understanding of the pathophysiology of neonatal circulatory failure and allow assessment of efficacy of inotropic intervention.

The published clinical trials have used varying definitions of efficacy, failure, and resistance based on different measures of virologic responses [ 15].

The events modelled following treatment failure due to lack of efficacy included titration to maximum dosage, within-class adjunctive therapy, between-class adjunctive therapy, and treatment switch.

Incidences of efficacy failure, graft loss or death or acute rejection within 6 months were not frequent and were similar between the drug groups.

Clinical treatment success (used for the cost-effectiveness ratio) and failure due to lack of efficacy, serious adverse events or mortality were possible clinical outcomes that could impact costs.

Late-stage clinical failures due to lack of efficacy or toxicity continues to be a challenge.