Despite the successful surgical treatment of the primary site, the presence of micrometastases, resistant to chemotherapeutic regimens, is responsible for the failure of the cure.
These are blatant instances of failure to cure, but unparalleled successes in bringing comfort to the terminally ill.
The probability of failure to cure PHPT by single-gland parathyroidectomy without IOPTH monitoring is a surrogate for the rate of unrecognized MGD in patients with well-localized disease.
When this benefit is weighed against the possibility of failure to cure and the associated morbidity, pain, surgical risks, complications, side effects, and costs, an effective dietary and nutritional protocol may present a reasonable alternative (Coley et al 1997).
There was criticism of his failure to cure Wigan's defensive problems but he will find Everton captain Phil Jagielka, Sylvain Distin, Leighton Baines and the ever-improving Seamus Coleman already in place and established as a very familiar unit.
This toxin/antitoxin system is likely to contribute to the stability of pVT1 and its presence may explain our failure to cure V. tapetis of its plasmid despite numerous attempts either by acridine orange treatments or by passages at sublethal higher temperature.
Ben Bernanke, then an academic and now the Fed's chairman, called the Bank of Japan's failure to cure deflation a case of "self-induced paralysis".Japanese lessonsIndeed, America's initial response to its own crisis and recession drew on the lessons from Japan.
Recently, the disease has spread to other continents because of population mobility and failure to cure the chronic disease.
Ependymomas (EPN) are enigmatic tumors which continue to present significant management challenges to clinicians as evidenced by the failure to cure up to 40% of cases [ 1].
The clinically evaluable (CE) population comprised c-mITT subjects who met all inclusion/exclusion criteria and had a clinical response of either cure or failure at the test-of-cure (TOC) assessment 8-50 days following the end of therapy (EOT).
