Sentence examples for failure of complement from inspiring English sources

Hence we have demonstrated no failure of complement immunity in HIV positive patients.

The association between complement or immunoglobulin deficiencies and CLL could be attributed to a failure of complement-dependent opsonization, resulting in an accumulation of apoptotic cells and a release of autoantigens that constitute a continuous stimulus for CLL clone proliferation (Fig.  3).

Multiple EMS-induced mutants, isolated on the basis of failure to complement the lethality of the P insertion chromosome, all had the blue phenotype in germ line clones (Douglas Ruden, personal communication).

Because we are interested in the allelic cases of failure to complement by using the E* and A* lines (as well as its inbred wild-type progenitor lines) in the tests, we control for most of the epistatic effects that can be caused by loci residing on chromosomes 2 and 3. Bonferroni correction was applied to control for multiple testing.

The following stocks were generated by standard meiotic recombination and isolated on the basis of their failure to complement other alleles and/or sequencing to verify the molecular lesion: NcadΔ14; elmbcD11.2spg242, mbcD11.2.

The recovery of CyO only progeny indicated failure to complement, and indicated the absence of a given gene within the deficiency.

To validate the identity of the molecular lesion responsible for the mutant phenotype, we tested candidates for RNAi phenocopy of the embryonic lethal phenotype or for a failure to complement a deletion allele of the candidate gene.

We observed failure to complement in 4 of the 24 tested deletions (Table 1).

Novel strategies are desired for treating heart failure, to complement the current use of ACE-inhibitors and β-blockers.

All but 5 of the 21 Arabidopsis CC-type GRXs exhibit this conserved C-terminus, the lack of which causes a failure to complement roxy1 (Li et al. 2009).

Although our results with Df(1 ED6906 and Df(1 C128 meet the requirements to be considered allelic failures to complement, these can also be interpreted as an epistatic failure to complement due to interactions of these deficiencies with other loci that affect CCRT residing elsewhere on the X or in the other two major chromosomes.