Sentence examples for failure of combination from inspiring English sources

If failure of combination regimens results from uncoupling, then similar results to those with alendronate are expected with denosumab.

In 2005, nab-paclitaxel was approved for the treatment of MBC after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy [ 2].

Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is indicated for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy.

Nab-paclitaxel has been approved by the US FDA in 2005 for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy.

Insulin initiation currently occurs in ∼5% of patients per year from diagnosis or first OAD prescription (74, 75, 76, 77), increasing to 10% per year following failure of combination OAD therapy (78).

Various treatment strategies were utilised during this period, including clozapine, following failure of combinations of other atypical antipsychotics and mood stabilisers.

After failure of the combination of a proton pump inhibitor (PPI), amoxicillin and clarithromycin –the most widely used combination in Spain–, quadruple therapy (PPI-bismuth-tetracycline-metronidazole) has been the most widely used treatment.

Interestingly, the failure of the combination prazosin plus rauwolscine to abolish (although markedly blocked) the DHE responses in ritanserin-pretreated rats (Fig. 4c) cannot categorically exclude the possible role of additional (although negligible) mechanisms, including an enhanced synthesis of proconstrictor prostaglandins by DHE, as reported by Müller-Schweinitzer [26].

In current practice it is used as rescue medication after failure of standard (combination) laxative therapy.

12 The importance of inflammation in regulating iron availability in COPD is illustrated by the failure of the combination of iron deficiency and hypoxia to suppress hepcidin completely in the ID COPD group, whereas it is barely detectable in the ID healthy controls.

More recently, however, a report from the German Breast Group suggested that response-adapted chemotherapy could be effective: breast cancer patients who received vinorelbine and capecitabine after failure of a combination of docetaxel, doxorubicin and cyclophosphamide (TAC) had a better survival than those who continued on TAC (von Minckwitz et al, 2013).