Sentence examples for failure of clearance from inspiring English sources

Functional deficiency of CD154, the ligand for CD40, leads to a failure of clearance of biliary tract infections and a predisposition to cholangiocarcinoma implying a direct link between TNF receptor-mediated apoptosis and the development of cholangiocarcinoma.

In a random-effects meta-analysis, ciclopirox produced failure of clearance of 21% (RR 0.79, 95% CI 0.67 to 0.94; I² = 81%) (Analysis 19.1).

There is delayed early neutrophil recruitment, failure of clearance of necrotic fibres and a prolonged inflammatory infiltrate that correlates with a delay in the recovery of contraction force.

At 14 days, the difference in the regenerative process between the two strains appeared more to relate to failure of clearance of necrotic tissue than the ability to form new desmin positive fibres.

In populations of people with Down syndrome who develop dementia and in those with early-onset Alzheimer's dementia, the characteristic brain lesions are hypothesised to develop because of various mechanisms leading to the overproduction of toxic changes and deposits, whereas in the older groups with Alzheimer's disease there is predominance for failure of clearance mechanisms.

All patients failing treatment, defined as reappearance of parasitemia after its initial complete clearance or failure of complete clearance within 28 days, were retreated whether they became symptomatic or not and after samples had been obtained for microscopy and PCR analysis.

An osmotic gradient that favors the rapid absorption of liquid from the CF airway surface ultimately results in the accumulation of dehydrated mucus in the airways and the gradual failure of mucociliary clearance.

Background: Abnormal glycosylation of immunoglobulin A1 (IgA1) has been implicated in the pathophysiological characteristics of IgA nephropathy, leading to failure of normal clearance mechanisms and mesangial deposition of serum IgA1.

Failure of phagocytic clearance of apoptotic and/or necrotic cells has been postulated as a possible driving force for sustained anti-chromatin autoimmunity [42], [46], [50], [51].

Profound T cell depletion and hypogammaglobulinemia may explain this failure of NoV clearance.

A newly developed theory proposes that failure of this clearance system underlies increased Aβ brain accumulation in AD.