Sentence examples for failure of activation from inspiring English sources

What Barkley sees as inhibition we see as a failure of activation, for which we provide a specific mechanism.

Further, under ANXA2 deficient, loss of plasmin leads to failure of activation of metalloprotease-9 and -13 near the migrating cell and may retard cell migration.

Therefore, the incapacity of these schedules to produce hypersensitivity might be due to a long time infusion rather than to failure of activation of the immune system (which presents a circadian rhythm) in a chronomodulate setting (Levi et al, 1994a).

We have found the majority of colorectal carcinoma cell lines are resistant to PPP treatment due to failure of activation of the intracellular AKT and ERK growth pathway and induction of the BAD-induced mitochondrial apoptosis pathway.

Finally, we also show in vivo that post-radiotherapy mitochondrial DNA copy number increase well correlates with lack of HIF1 α increase in the tissue, concluding this may be a useful molecular tool to infer the trigger of a hypoxic response during radiotherapy, which may lead to failure of activation of cell senescence.

They suggested that a combination of muscle atrophy and failure of voluntary muscle activation explained 85% of the loss of quadriceps strength, but that the failure of activation was the dominant factor, explaining twice as much of the variance as the muscle atrophy.

These observations further imply that downregulation of C1q enhances prostate hyperplasia and cancerous formation due to failure of WOX1 activation and increased activation of STAT3.

It was therefore important to establish whether GC resistance resulted from the failure of Bax/Bak activation, or failure of activated Bax/Bak to induce downstream apoptotic events.

Altogether our data suggest a failure of mTOR activation by amino acids or ER stress activators to further upregulate GRP78 in the brain of PGC-1β KO mice.

Taken together, these findings suggest that the GC-induced killing of CLL cells results from the indirect activation of Bax and Bak by upregulated Bim/Bcl-2 complexes, and that GC resistance results from the failure of such activation to occur.

Fewer turns can indicate loss of motor units or failure of central activation of contraction, whereas greater amplitude can indicate reinnervation after nerve damage.