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We examined a small number of high-scoring PSMs where ProPhosSI fails to validate an assignment made by an experienced analyst.
From your explanation I expected that the only way something can be a "false positive" is if it gets called imprinted from RNA-seq data, but fails to validate with pyroseq data.
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Using Hh and Wnt signaling pathways as examples, we find that the validation experiment indeed failed to validate some of the known pathway regulators.
They need the law to fail to validate their enmity.
The experimental results for constrained and unconstrained benchmark functions under fairly equal conditions failed to validate its performance supremacy.
An obvious way was by replicating the methodology of the research studies, and in doing so I found that the people I worked with also failed to validate their communication.
Despite a careful replication study design, we failed to validate the initial findings for any of these variants, with the possible exception of MAPT, SORL1 and TFCP2 for which some nominal but inconsistent evidence of association was observed.
Our evaluation shows that 10-year increment bias is substantial, almost 17% on average, and our tests failed to validate the model for every one of the 30 most common tree species in the region.
Using the given judgement bias test design we have failed to validate it as a tool for the assessment of changes in affective states induced by housing conditions in Japanese quail.
Webb doesn't come down on either side of the argument, but instead leaves you with the following quote from the book Thinking-based Learning by Swartz et al. "A presidential commission concluded that various U.S. intelligence agencies failed to validate the reliability of their sources in assessing pre-war conditions and events in Iraq.
Similarly, virtual21 and real lesion studies failed to validate an exact correspondence between language impairments and information represented in the frontotemporal speech network: damage in one area may, or may not, entail loss of function in the other, as even sub-regions within such well-known perimeters appear to support different functions22,23,24,25.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com