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The decrease in the sensitivities of all methods can be explained by the fact that the alignment tool fails to align increasingly noisy RF reads.
After assembly, the intron/exon junctions were visually inspected and adjusted to ensure proper alignments, particularly for intron splice sites, as software frequently fails to align the A-Trich sequences properly.
Billing by the hour often fails to align lawyers' interests with their clients'.
And because it is an externally developed assessment, which the teachers say largely fails to align with district and state standards (N.W.E.A. disputes this point), there is no preparation for it.
"India will lose significant ground as a destination for international investment if it fails to align itself with policy and practice around the world," it added.
By drawing on critical insights from behavioural economics and psychology, we illuminate the key cognitive biases and motivational factors that may explain why energy-related behaviour so often fails to align with either the personal values or material interests of consumers.
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Automated alignments have failed to align the region N-terminal to the equivalent of Ser806 critical for ATP binding.
Especially in scenarios where some of the input genomes have undergone whole-genome duplication, the positional homology alignment method may fail to align many target regions.
A noteworthy aside is that default alignment parameters often fail to align fungal repeats correctly due to complex internal repeat structures.
These splice junctions are either altered by a nucleotide change, fall in a region of sequence expansion/contraction, or are not represented in the alignment because the exons failed to align.
In addition, 816 segments with sequence in both genomes failed to align with LASTZ and also failed to produce consistent alignments with different Smith Waterman alignment implementations.
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