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When you are on the Internet, stick to more listening to music, looking up funny jokes and pictures, watching YouTube, and if everything else fails, study.
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Unfortunately, however, they are too often overinterpreted or misused in the hope of resurrecting a failed study.
Only 1 patient in each group actually failed study treatment.
Thirty-six patients (78%) who failed study treatment received the next-line chemotherapy.
All patients with MRSA bacteremia were cured and one patient with MSSA bacteremia failed study treatment in each group.
These can be uncomfortable and awkward, resulting in patient motion and failed studies.
The number of failed studies could probably be reduced significantly by applying more informative outcome measures.
And just last week, Uri Simonsohn released a paper on coping with the famous file-drawer problem, in which failed studies have historically been underreported.
If this is in fact true, then you need to provide reliable information, not information from failed studies over the course of 40 years.
Even failed studies include patients who derived benefit; they should be investigated to identify features distinguishing the tumors and host environment of responders from non-responders.
Both failed studies followed optimistic observational research and animal work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com