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A histidine or cysteine at position 6 led to peptides failing to bind to FluB PA, while binding to FluA PA was still possible, indicating that not all amino acid substitutions confer the dual-binding activity observed with tyrosine at this position.
Nor did gH-specific mAbs block binding-MG-4A12 provides a representative example-consistent with gH-Fc failing to bind GAGs (Fig. 1B).
Remarkably, PRR-2 bound IP3 with low nanomolar affinity while failing to bind another second messenger, adenosine 3′, 5′-cyclic monophosphate (cAMP).
Some say he is failing to bind the United States to the historic change under way in the Middle East the way that Ronald Reagan forever cemented himself in history books to the end of the cold war with his famous call to tear down the Berlin Wall.
Parks spurned a chance to level in the 16th minute, pulling his kick to the right of the posts after Treviso were penalised for failing to bind at the scrum.
The phenotype induced by a FOXP3 mutant failing to bind RUNX1 is characterized by a loss of suppression and abrogation of CD25 induction [21].
Similar(48)
Thus although the mature bnAbs bind to conserved epitopes of the HIV-1 envelope glycoprotein (Env) with high affinity their germline predecessors do not or weakly bind Envs failing to initiate an effective immune response.
And failing to provide that leadership is bound to lead to the very outcome the Obama administration has been trying to avoid: intervention.
The nightly "visuals" - as Home Secretary David Blunkett calls them - of asylum seekers failing to leap aboard Eurostar trains bound for Dover have sparked calls to tighten the United Kingdom's border controls.
Two clones bound to the HMGB1 box A, the other two could only bind to the box A+B, failing to recognize the box A or box B (Fig. 2B).
And under the Indian Penal Code, failing to provide a document one is legally bound to provide to a public servant, the punishment can be up to one month's imprisonment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com