Sentence examples for failed to further improve from inspiring English sources
To summarize, CR reduced body weight in both phenotypes and improved fasting insulin sensitivity in normal mice, but failed to further improve the already insulin-sensitive status of GHRKO mice, thus uncoupling the effects of CR on body weight/growth from its effects on insulin sensitivity and lifespan.
Extending the durations of spontaneous recovery failed to further improve knee extension (P > 0.05, all 12 comparisons).
We noticed that repeated 17-DMAG administrations at 10 mg/kg failed to further improve the mouse survival after irradiation.
Although canakinumab appeared to improve clinical scores, based on our simulations, increasing dose levels beyond 150 mg (up to 900 mg) failed to further improve outcomes.
At present, the combination of paclitaxel and carboplatin is the most widely used chemotherapy regimen, and produces a median survival of ∼36 months 1, 2. Although other cytotoxic agents have activity against ovarian cancer, their addition or substitution in the first-line paclitaxel/carboplatin regimen has failed to further improve results.
This convergence between normal mice exposed to long-term CR and innately insulin-sensitive GHRKO mice could explain why CR fails to further improve insulin sensitivity of GHRKO mutants or further extend their already-long lives.
Pre-ischaemic δ-OR agonism with BW373U86 improved recoveries in CD hearts in association with phosphorylation of Akt (+40%), eNOS (+75%) and GSK3β (+30%), yet failed to further enhance RISK-NOS activation or I-R outcomes in OB hearts.
Dithiothreitol failed to further reduce HyPer or to induce reasonable FLIM and two-photon responses.
We have also applied the newly developed two-phase thermodynamic (2 PT) approach in an attempt to further improve the results but failed.
However, the yield strength of the composite failed to be further improved when adding too much B4C because of the agglomeration of the reinforcements.
