In an accompanying editorial, Dr. Harold Sox, editor of The Annals, wrote that his interpretation of an analysis of several large randomized clinical trials in Sweden was that they also failed to find a benefit from mammography in women under 50.
A recent meta-analysis of IP for liver resection in patients with and without chronic liver diseases failed to find a significant benefit of IP in liver resection [ 115].
But arguments against the annual physical for all adults have been fueled by a growing number of studies that failed to find a medical benefit.
"The general, overall picture is that they failed to find a big benefit," for Infuse, Dr. Krumholz said.
Both trials failed to find a significant clinical benefit with the addition of celecoxib to the exemestane regimen, despite earlier indications in small feasibility studies that there could be increased efficacy for the combination [ 13, 14].
The majority of MEPs failed to find a solution that would have benefitted consumers and creators," she added in a statement.
14 The team developed a complicated equation to calculate the payment levels, but failed to find a suitable fee to apply to tourist companies benefiting from the landscape beauty of the forest.
Some studies have found a moderate benefit of vitamin C in reducing the duration and severity of common-cold episodes, but numerous studies have failed to find a significant effect on incidence.
Dedicated trials failed to find a significant reduction in CVD outcomes in a diabetic population treated with fenofibrates, [ 26] while meta-analyses conducted upon pre-specified subgroups have confirmed the clinical benefits of fibrates on major CVD events [ 27, 28].
