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Variants that failed to be called in all individuals were excluded.
Except IL12B and JAK2, the other 5 genes also failed to be called by [ 14].
Any base that failed to be called by the sequencer, typically marked as an "N" in a read, is neglected.
Initial peak-calls from the 5-replicate pool were discarded if they failed to be called in any of the 4-replicate pools (SSI test).
There are 4 genes, C13orf31, MST1, RTEL1 and HLA-DQA2, that were listed on top 150 by [ 14] and failed to be called in our study.
There are 7 genes identified as association candidates in our study, which failed to be called by GWAS p value ranking, they are PTPN22, IRF1, PTGER4, IL12B, IL18R1, FASLG and JAK2.
Similar(52)
Asif, with his tact and greater experience would bowl a no-ball which could not fail to be called, but only inches over the popping-crease".
The use of T2 would change the genotype composition for 12 individuals, with a total of 17 variants that would fail to be called 'putative alleles'.
A gene with high posterior score can be called as candidate genes, even though it has a low prior score and fails to be called in standard GWAS due to stringent p value cut-off, chip coverage or sampling bias.
Comparison of the DS values clearly indicated that when well-performing SNPs (i.e. those with low "NoCall" rates) fail to be called they do so primarily because of the detection filter, while the majority of poorly performing SNPs fail for other reasons.
Determined to move up, Caroline applied for good office jobs and, when she failed to be hired, called to find out why.
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