Sentence examples for failed to abrogate from inspiring English sources
However blockade of GSK-3β, another PI-3K target, failed to abrogate Aβ-induced shrinkage of Homer1b and Shank 1 clusters (data not shown).
In the presence of heat shock, dorsomorphin diminished the effect of bmp2b induction on hepcidin expression six-fold, but failed to abrogate it.
The addition of TPZ to the culture medium failed to abrogate the expression of HIF-1α in aerobic HeLa cells (Fig. 5A).
However the INrs failed to abrogate the inhibitory effect exerted on IN by LEDGF-derived inhibitory peptides and Fig 3C and D), again emphasizing the specific interaction between the INrs and the Rev protein and peptides.
On the other hand, the INr peptides failed to abrogate the inhibitory effects of two LEDGF derived peptides [36], strengthening the view that the abrogation is due to specific interactions of the INr peptides with the Rev protein or Rev derived peptides.
Mice treated with mAb against CD4 or CD8 T cells failed to abrogate the antitumor activity (P > 0.05).
The present observations indicate that the initiator caspase-10 is involved in FasL-induced cell death and the broad-spectrum pancaspase inhibitor zVAD-fmk fails to abrogate caspase-10 activity.
At this point in the discussion, we believe that subset receptor editing fails to abrogate autoreactivity or polyreactivity in the unmutated CLL; however, in some mutated CLL subsets, receptor editing/revision has successfully worked to avoid self-reactive BCRs.
But recognition of misfolded htt by gp78 still requires the cue domain, since mutation of the cue domain that abrogates gp78-htt interaction failed to target mutant htt for degradation.
However, following DHPM treatment at different concentrations (30 μM, IC50 and 300 μM), the intercellular connection was abrogated and HUVEC cells failed to form tubes.
In addition, locked nucleic acid (LNA -mediated knockdown of RasGRF1 abrogated MMP-3 LNA -mediatediled to affect MMP-1, thus demonstrating disparate regulation of these two MMPs.
