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Unfortunately, however, they are too often overinterpreted or misused in the hope of resurrecting a failed study.
Only 1 patient in each group actually failed study treatment.
Thirty-six patients (78%) who failed study treatment received the next-line chemotherapy.
All patients with MRSA bacteremia were cured and one patient with MSSA bacteremia failed study treatment in each group.
All patients with MRSA bacteremia were cured, and one patient with methicillin-resistant S. aureus bacteremia failed study treatment in each treatment group (Table 4).
"This is a failed study," declared a member of the trade group's panel, Dr. Lewis Kuller, an epidemiologist at the University of Pittsburgh.
Similar(51)
And just last week, Uri Simonsohn released a paper on coping with the famous file-drawer problem, in which failed studies have historically been underreported.
And, of course, the unwritten rule that failed studies — the ones that find no effects — are far less likely to be published than positive ones.
Both failed studies followed optimistic observational research and animal work.
The number of failed studies could probably be reduced significantly by applying more informative outcome measures.
Even failed studies include patients who derived benefit; they should be investigated to identify features distinguishing the tumors and host environment of responders from non-responders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com