Crucially, when cells exited mitosis after downregulation of both separase and Plk1, centriole disengagement failed completely, and subsequent centriole duplication in interphase was also blocked.
To step back, the CA DMV classifies a disengagement as any event where a human safety driver has to assume manual control of the vehicle in order to 1. intervene in the interest of safety, or 2. take control because the AV system has failed or disengaged on its own.
Students who failed Algebra I exhibited greater school disengagement warning signs during ninth grade in terms of attendance and discipline issues.
What concerned the administration, officials said, was Mr. Sharon's stated intention to carry out the disengagement plan in a few months if the Palestinians failed to carry out the steps called for in the peace plan.
But what we see worldwide is employee disengagement, high levels of leader turnover and career derailment, and failed leadership development efforts.
[It also] failed to tackle an insidious negative culture involving a tolerance of poor standards and a disengagement from management and leadership responsibilities," he said.
Political leaders in Macedonia failed last week to agree on a package of political reforms that diplomats had hoped would lay the groundwork for a disarmament of the rebels and disengagement of the government forces.
It was Sharon's most specific disclosure about what he calls "unilateral disengagement" from the Palestinians, a step that he has said he will take if he judges that the Bush administration's peace initiative, known as the road map, has failed.
It was Mr. Sharon's most specific disclosure to date about what he calls "unilateral disengagement" from the Palestinians, a step he has said he will take if he judges that the Bush administration's peace initiative, known as the road map, has failed.
Both approaches — unconditional engagement and unconditional disengagement — are likely to fail.
