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For those replications that fail to replicate the results of the original study, a second replication should follow the first.
Most mutations that were predicted to disrupt the secondary structures fail to replicate, while compensatory mutations were allowed replication to resume.
This is one reason why many studies fail to replicate.
Many rodent models fail to replicate both MetS and NASH.
A paper can be seriously flawed and fail to replicate but still contain valuable insight.
They might die, refuse to engraft or fail to replicate and differentiate.
Studies are particularly likely to fail to replicate if they were based on a small sample.
Even the most prestigious scientific journals are publishing papers that fail to replicate and which, in retrospect, are simply ridiculous.
Even if R.I.M. does a lot of things right, it could still fail to replicate Apple's success with tablets.
Smaller studies are more likely to fail to replicate in part due to chance, but effects may also be smaller as sample size increases, for several reasons.
And even if his offspring fail to replicate his success, they can always be sent to stud themselves to help earn back their cost.
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