Sentence examples for fail to mediate from inspiring English sources
Our observation that CLIP-identified non-canonical sites fail to mediate repression reasserts the primacy of canonical seed pairing for miRNA-mediated gene regulation.
In previous studies, we found that AnxA2 knockdown selectively inhibits the transport of endocytosed tracers from early to late endosomes: newly-formed multivesicular endosomes do not detach from early endosomes, and thus fail to mediate transport towards late endosomes [15].
Why might the CLIP-identified non-canonical sites fail to mediate repression despite binding the miRNA in vivo?
However, we have previously demonstrated that other strains of L. plantarum (Lp IBDML1 and other strains), which can colonize efficiently the larval gut and the nutritional environment, do fail to mediate juvenile growth promotion (Storelli et al., 2011) (G.S. and F.L., unpublished data).
In our studies, library-derived vector capsids (displaying RGDLGLS, DGLGRLV) selected on primary murine breast cancer cells in vitro transduce the cell type they were selected on with high efficiency but fail to mediate breast cancer tissue directed gene transduction after systemic administration.
Mr. Simmons has criticized Mr. Gejdenson on the tribal lands issue, saying he has failed to mediate between the tribe and the towns that oppose expansion.
The United States and Yemen's Arab neighbors like Saudi Arabia, which have tried and failed to mediate a peaceful solution to the country's political crisis, are reduced to sitting on the sidelines and pleading for restraint.
In males, both negative and positive outcome expectancies failed to mediate impulsivity and alcohol related problems.
Like hostility, anger successfully predicted bullying perpetration but unlike hostility it failed to mediate the victimization perpetration association.
Britain failed to mediate as it had done in the previous Balkan crisis out of fear of Germany's European and global ambitions - a fear that was not entirely rational since Britain had clearly won the naval arms race by 1910.
Although obese animals and humans frequently have elevated circulating leptin levels, their leptin fails to mediate weight loss, implicating resistance to the action of leptin in obese states.
