Sentence examples for fail to interact from inspiring English sources

Our results show that mutant ΔPP polypeptides fail to interact with endogenous dFMRP, suggesting that self-interactions of dFMRP and/or its interactions with endogenous dFMRP, are essential for granule formation.

It is also plausible that AtCRT1a and CRT3 are unable to efficiently fold different Ca2+-releasing components in the ER, or that AtCRT1a and CRT3 fail to interact with these components that may require a direct interaction with CRT to facilitate Ca2+-signaling.

Under these conditions, dissociation of an interaction provides a selective advantage, thereby facilitating detection: a few growing yeast colonies in which hybrids fail to interact can be identified among millions of non-growing colonies expressing interacting proteins.

We believe that the PB1/PA interface is an excellent target for PPI inhibitors, because the PA-binding domain within the extreme N-terminus of PB1 is crucial for the interaction with PA, since PB1 mutants lacking this domain fail to interact with PA [28].

This indicates that not only does Hsc70 K71M fail to interact with ICP27, but also that it appears to interfere with the interaction of endogenous Hsc70 and ICP27.

"I have always had a fascination with the way people interact, or in this case fail to interact, which inspired the photograph of this group of girls," he said.

As in MEFs, the MUS81 loss-of-interaction mutants failed to interact with SLX4 in co-immunoprecipitation experiments (Fig. 2C).

In yeast, the LGMD2H mutant TRIM32 D487N failed to interact with dysbindin, whereas a robust interaction between TRIM32 P130S and dysbindin was found (Fig.  1B).

The observed interactions are specific, as H2A nucleosomes failed to interact with these two factors.

Importantly, other members of the sirtuin family failed to interact with MeCP2e1, underscoring the specificity of the SIRT1-MeCP2 interaction (Fig. S2B ).

Consistently, UXT-2M failed to interact with either NICD or RBP-Jκ, indicating the functional relevance of the interaction between UXT and NICD.