Suggestions(2)
Exact(11)
However, drastic and persistent perturbation of the parkin/p62 axis, would redefine a threshold where proteins fail to degrade, neuronal signaling is impaired, and the hallmarks of PD are manifested.
Such a phenotype is characteristic of nuclear exosome mutants that fail to degrade aberrant nuclear RNAs [39].
Silencing mutants should fail to degrade cyclin B upon ark1-as3 inhibition.
These cells fail to degrade FLIP following T-cell activation and/or IL-2 stimulation.
8, 9 These effects have been largely attributed to phagocytic cells that fail to degrade the DNA of apoptotic cells.
He suggested that lysosomes gradually accumulate lipofuscin and that the lipofuscin granules attract lysosomal enzymes which, however, fail to degrade the pigment.
Similar(49)
In fact, according to the Pentagon's own evaluations, American bombing failed to degrade Slobodan Milosevic's forces.
A report by the Afghanistan NGO Security Office pointed to a 59% increase in Taliban attacks in the third quarter compared with the same period in 2009, and said the surge had "failed to degrade [the Taliban's] ability to fight".The government may share that view.
Although the absorbance of the diffuse reflectance spectrum of NiFe2O4 extended to 788 nm, NiFe2O4 failed to degrade organic dyes in the presence of H2O2 despite white light irradiation containing ultraviolet light.
In the South, despite more robust efforts from the US NATO contingents, counterinsurgency operations in Kandahar and Marjah have similarly failed to degrade the IEA's ability to fight, reduce the number of civilian combat fatalities (p.13) or deliver boxed Government".
(B ) His C mutant embryos failed to degrade Cyclin A. (C – H ) Magnifications of epidermal cells from embryos.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com