fail the assay

USAGE SUMMARY

The phrase "fail the assay" is correct and usable in written English.
It can be used in contexts related to scientific testing or analysis, particularly in laboratories or clinical settings, to indicate that a sample did not meet the required standards or criteria. Example: "The results showed that the sample failed the assay, indicating a potential issue with the quality of the substance."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

Previous studies from our laboratory have reported APEX genotyping accuracies ranging from 98%to99.8%8% [ 14, 16- 18], though the call rates in these studies have always been significantly lower than 100%, and usually do not include a proportion of the originally selected SNPs that fail the assay.

BMC Medical Genomics

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

**The SNP rs1966265 failed the assay and the rs12519145 was genotyped instead (r2 = 0.8).

BMC Cancer

Illumina Goldengate SNPs with pre-optimized assays were chosen where possible, however roughly 10% of the chosen SNPs failed the assay design.

Human Molecular Genetics

Three variants failed the assay, and any SNP with total genotype counts < 10 in the heterozygous and rare homozygous groups combined (n = 9) was excluded from further analysis.

American Journal of Clinical Nutrition

Post-marketing surveillance which resulted from this study found 39 of 40 (97.5%) and 38 of 40 (94.9%) injectable oxytocin and ergometrine samples, respectively, failed the assay for API or a sterility test.

BMC Pregnancy and Childbirth

Of 164 variants (92 tagSNPs, 72 others) advanced into next stage, 30 failed the assay design for genotyping (23 tagSNPs, 7 others) and 2 suspicious variants turned out to be monomorphic after genotyping (indicating sequencing artifacts).

European Journal of Human Genetics

Briefly, the tag-SNPs (minor allele frequency > 0.05) were selected using the Tagger program of (r>0.8), which combines the simplicity of pairwise r2 methods [ 40] with the potential efficiency of multimarker haplotype approaches [ 41]. *The SNP rs1966265 failed the assay and the rs12519145 was genotyped instead (r2 = 0.8).

BMC Cancer

It is recommended to accept the results from SNP assays with Silhouette scores >0.65, to fail the whole assays if the Silhouette scores is <0.25 and to manually inspect the assay results if the score is included in the [0.25; 0.65] interval.

Plosone

Based on the results from the scatter plots used to assign genotypes in this study, our recommendation is to accept the results from SNP assays with Silhouette scores >0.65 and to fail the whole assays if the Silhouette scores is <0.25.

BMC Genomics

Among the 130 whole saliva samples collected, 5 failed the pyrosequencing assay for CYP19A1 and 1 for PPARG, leaving 125 and 129 samples, respectively, with methylation data.

BMC Pediatrics

Eighteen of these failed the genotyping assay or were uninformative, thus 69 SNPs remained for further analyses (Supplementary Table 1) (genotyping was performed by LGC Genomics Ltd ,Herts, EN11 0WZ, UK).

Heredity

Expert writing Tips

Best practice

When reporting assay failures, clearly state the reason for the failure (e.g., contamination, technical issues, design flaws) to provide context and facilitate troubleshooting.

Common error

Avoid assuming an assay failure automatically indicates a problem with the sample itself. Technical issues, reagent quality, or procedural errors can also cause an assay to "fail the assay".

Linguistic Context

The phrase "fail the assay" functions as a verb phrase indicating that a specific test or procedure did not meet the required standards or produce valid results. Ludwig AI confirms this is grammatically correct and usable. It is frequently found in scientific contexts.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "fail the assay" is a grammatically correct and usable term, predominantly found in scientific literature, as confirmed by Ludwig AI. It serves to report that a test did not meet required standards. When reporting an assay failure, it's crucial to state the reasons for failure. Common errors include assuming the sample is always the issue when technical problems might be the cause. Alternative phrases include "assay failure" or "test failure". The register is formal and scientific.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

assay failure

Focuses on the result rather than the process.

test failure

Broader term applicable to various types of tests, not specifically assays.

assay invalidation

Emphasizes the act of making the assay results void.

the assay did not pass

Uses a more direct and active voice.

the assay yielded an unacceptable result

Highlights the negative outcome of the assay.

the assay was unsuccessful

Focuses on the lack of success in achieving the intended result.

the assay produced a false negative

Specifies the type of error that occurred during the assay.

the assay produced a false positive

Specifies the type of error that occurred during the assay.

the assay did not meet quality control standards

Emphasizes the failure to adhere to predetermined quality benchmarks.

the assay was deemed unreliable

Focuses on the lack of dependability of the assay.

FAQs

What does it mean when an assay "fail the assay"?

When an assay "fail the assay", it means the test did not produce valid or reliable results, often due to technical issues, sample problems, or design flaws. This necessitates further investigation or retesting.

What are some alternative ways to say "fail the assay"?

You can use alternatives like "assay failure", "test failure", or "the assay did not pass" depending on the context.

How do I report an assay failure in scientific writing?

Clearly state that the assay "fail the assay", and provide a concise explanation of the potential reasons for the failure. Include details about any troubleshooting steps taken or recommendations for future testing.

What steps should I take if my assay "fail the assay"?

First, review the assay protocol and ensure all steps were followed correctly. Check for potential contamination or reagent issues. If the problem persists, consult with experienced colleagues or consider optimizing the assay protocol.