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Some patients fail hearing screening tests in the first year, and speech delay is not unusual in more severely affected patients.
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Some 66% failed eye screening, 22% failed hearing screening, 46% had untreated dental decay, 69% had gait abnormalities, 20% needed a follow-up hearing test, 15% needed urgent dental treatment, 8% had raised blood pressure and needed urgent followup.
Results Six hundred twenty-five patients were analyzed; 45 neonates failed hearing screening.
Treatment with aminoglycoside antibiotics in combination with mitochondrial m.1555A>G mutation was tested as a predictor for failed hearing screening at discharge in a multivariate logistic regression analysis.
*Defined as mean of air conduction threshold values at 0.5, 1, 2, and 4 kHz ≥30 dB in worse affected ear among participants who failed hearing screening test.
Originally he tried to enlist as a fighter pilot but failed hearing tests.
However, only 3 out of 10 preterm m.1555A>G-carriers m.1555A>G-carrierso aminoglycosides failed hearing screening.
Percentage of failed hearing screening for each category is given in Figure 1.
Low birth weight was the most significant predictor of failed hearing screening (p = 7.3 × 10-10).
Low birth weight was the most important predictor of failed hearing screening (OR 0.91, 95%CI 0.88-0.94 per 100 g additional birth weight, Figure 1).
Multivariable analyses performed exclusively on preterm neonates indicate that assisted ventilation lasting >5 days is an independent risk factor for hearing loss and a risk of failed hearing screening tests [ 74, 90].
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