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But even as details pour in about John Allen Muhammad and John Lee Malvo and about the sudden coalescence of facts binding them to the sniper attacks, the pall over life in the Washington area has begun to lift.
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In fact, binding of bivalent ligands shows a considerable avidity effect; affinity of a dimeric myosin 5a fragment has been recently reported to be ∼40 nM [20].
This confirms that the compounds are in fact binding at the AF2 site.
In fact, binding of LPS to collagen type II can significantly be reduced by antibodies against collagen type II.
In fact, binding of either ATP or ADP to PKA critically depends on Mg2+ ions (23, 32, 34, 35, 47).
If Kaiso is in fact binding methylated DNA, it is likely doing so via the Kaiso methylated motif (because the unmethylated motif does not contain a CpG).
In fact, binding sites for other transcription factors have been found close to replication origins and have been implicated in origin activation in both yeast and mammals [ 39– 42].
In fact, binding of UDG to its AP site result in the inactivation of UDG activity because the dissociation of UDG from the AP site by APE1 is a rate-limiting step.
Chromatin immunoprecipitation assays in myeloid leukaemic cells confirmed that CEBPA is, in fact, binding in vivo to this part of the pri-miR-29a/b1 locus as suggested by the luciferase experiments: both endogenous CEBPA in U937 cells and exogenous CEBPA in Kasumi-CEBPA-ER were binding to the CEBPA site located +15 to +29 bp downstream of the pri-miR-29a/b1 transcript start.
That gives us the scope to use this Charter to check whether the Member States are observing the provisions relating to human rights, which are in fact binding and which are included in innumerable conventions of the United Nations, the Council of Europe, the ILO etc. Human rights are universal, indivisible and interrelated.
In fact, bindings of many TFs are tissue specific and condition dependent.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com