Exact(7)
Different promoters respond to different environments, and regulate factors to function with appropriate splicing variants.
Recently, the Jordan group hypothesized that L1 elements tend to be enriched far from transcriptional start sites of genes and depending upon the kind of repeat, some may recruit epigenetic factors to function as gene regulators to nearby genes by opening or closing the local chromatin to transcription factors [33], [34].
Thus, Rpi1pSigma must be structurally different from Rpi1pS288c and require additional factors to function.
For transcription factors to function correctly, they must be able to reach the stretch of DNA where they bind.
The single AP1 site in the MMP-1 promoter was not sufficient, suggesting that it normally requires the binding of other factors to function fully.
This is consistent with previous studies that find these transcription factors to function as major regulators of senescence [ 29, 32– 32].
Similar(53)
Two recent studies [ 4, 5] have revealed that components of the spliceosome are essential for MYC (a transcription factor) to function as an oncoprotein.
IAP is probably only one of many contributing factors to renal function, and it will be hard to dissect consequences of a slight chronic increase in IAP from other factors related to renal function loss [31].
Previous studies have demonstrated the important contribution of pluripotent transcription factors to CSC function.
These included several HoxA genes as well as 19 transcription factors known to function as regulators of HSPCs [25].
Second, few studies have examined demographic, psychosocial, deployment experiences, and physiological factors contributing to function after deployment.
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