Sentence examples for factor with a critical from inspiring English sources

Olig2 is a bHLH transcription factor with a critical role in both motor neuron and oligodendrocyte specification.

Using 1000 random permutations of the data, observed eigenvalues exceeded the 95th centile of this null distribution up to the 16th factor with a critical eigenvalue of 0.556 and 104% variance explained.

Taken together, these findings suggest that FUS-DDIT3 could prevent the development of committed adipocytic precursors in liposarcoma through the interference with PPARγ and C/EBPα expression, two transcription factors with a critical role in adipogenesis.

Because complete elimination of β-h/c by targeted mutagenesis is known to diminish GBS resistance to phagocytic killing (16 ) and to reduce blood survival in a variety of animal models (10, 12, 14, 16 ), the results imply a simultaneous up-regulation of a factor with a more critical role in phagocyte resistance in the LH variant.

Instead than eliminating altogether the use of bibliometric indicators, [10] such as the h index or the impact factor, we agree with a critical approach to expand and improve their use in a useful and wise manner.

We use the antibody to demonstrate that linear polyUb is up-regulated upon tumor necrosis factor α stimulation of cells, consistent with a critical role in nuclear factor κB signaling.

The dynamic interaction of these biological and environmental variables along with experiential factors plays a critical role in defining subjective aspects of stress (i.e., the perception and appraisal of a stressful event) and alcohol intoxication.

Therefore, the escape room business model is fraught with a critical limiting factor.

Each specific type of interaction a physician has with an electronic health record could be associated with a critical adoption factor and the latter with a role of information and communication technology in the knowledge management processes; this association helps physicians to support an adoption decision in an automatic manner.

We focused on PA because of the rising importance and modifiability of this risk factor with regard to critical geriatric syndromes such as functional decline, falls and disability.

Furthermore, several of these factors are reduced after treatment with glucocorticoids, a critical component of CRS medical management.