Synergistic binding of multiple transcription factors to certain combinations of binding sites is an important mechanism of achieving highly specific regulation of genes in particular cellular conditions.
This site specificity suggests a targeting mechanism that guides general demethylation factors to certain CpGs.
These experiments involved introducing lineage-associated transcription factors to certain cells.
Yet, specificity of virulence factors to certain bacterial and strains is poorly understood.
Gene expression in eukaryotes takes place in the context of chromatin, which essentially acts as a physical barrier to the binding of transcription factors to certain genomic regions.
In our study, we summarized an HR from individual articles based on the SUV threshold used in each particular study, which helped to cancel the threshold factor to a certain extent.
Individual and work-related factors may to certain explain these findings.
Another study examined the possible association between cancer and environmental or social factors relevant to certain areas of central Sudan.
However, aside from virulence factors specific to certain organisms, differences are also detectable in association with broader microbial classifications.
In addition to the fact that CXR is unable to distinguish 'smear-positive TB' from 'smear-negative TB', all above-mentioned factors contribute to certain degrees of over- and under-diagnosis.
