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We chose to pool the adjusted effect measures rather than the crude ones because of the role of confounding factors on the validity of observational studies.
Further studies including vignettes should investigate the influence of such factors on the validity of self-reported health in this population.
Further studies including vignettes should investigate the influence of contextual factors on the validity of self-reported health in this population.
37, 38 These so-called skip metastases, a tumor-negative SLN combined with a positive non-SLN, are an important limiting factor to the validity of the SLN procedure.
Nevertheless larger studies are needed in order to identify crucial factors for the validity of the self-ratings of individual patients.
As well, specificity of the antibody to the analyte of interest is the limiting factor in the validity of the assay.
The specificity of the antibody to the analyte of interest is the limiting factor in the validity of any immunoassay system.
The experience of the arthroscopist is another important factor in the validity of cartilage lesion grading.
Methodological rigor is a fundamental factor in the validity and credibility of the results of a meta-analysis.
However, while the classification and selection of teams according to ID intensity are crucial factors in the validity of such studies, few tools finely evaluate teamwork intensity [ 2, 31].
24 25 Indeed, the relative contribution of each factor and the validity of cut-off scores for classifying at-risk individuals appears to vary substantially between study samples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com