It is of interest that these studies utilized the same protocol, yet realized such different rates of hypoglycemia, demonstrating that factors outside of the protocol rather than the glucose target may significantly influence glucose control and hypoglycemia.
47 Despite numerous studies, multiple factors of the feeding protocol, such as the time of initiation, method of administration and advance rate still remain controversial, and further trials are needed for protocol optimisation.
Theorem 1 gives a theoretical bound of the stretch factor of CSR protocol.
We first identify the factors influencing the performance of the protocol by modelling the establishment mechanism.
During our simulations the long-range hydrogen bonding term was weighted by a factor of one while the short-range term was weighted by a factor of 0.5, following the protocol used by the Baker group in CASP 7. If these terms were weighted more heavily relative to the rest of the potential a stronger bias towards the native state could arise.
The authors defined a scalability factor of routing protocol in terms of its total overhead and minimum traffic load.
Other important additional factors that reflect the integrity of the protocol will be addressed in the interim report.
Given that we just need to apply N of these gates per MS gate as shown in previous section, and we can reduce the time of each gate by about 3 orders of magnitude, for N = 40 one could reduce the time of the protocol a factor 25, well below the decoherence time.
KR provided PhD supervision and participated in the development of the study design and manuscript development, ALM participated in the development of the study design, provided information regarding prognostic factors, and contributed to the development of the protocol manuscript.
All acquisitions were performed with parallel acquisition (SENSE) enabled, with a SENSE factor of 2. The MRI protocol consisted of transverse and coronal T2 and proton density weighted (PDW) acquisitions of the knees.
