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Persistent infection with high risk Human papillomavirus (HPV) is the main aetiological factor in the development of cervical cancer.
Other bacteria, Chlamydia trachomatis (Ct), infection acts as a risk factor in the development of cervical lesions.
Polymorphism of the p53 gene, codon 72, is also considered a risk factor in the development of cervical carcinoma.
The most important risk factor in the development of cervical cancer is infection with human papilloma virus (HPV) [ 8, 37, 43].
Infection with high-risk human papillomavirus (HPV) is now known to be a necessary aetiological factor in the development of cervical cancer (Munoz et al, 2006).
It is well-established that persistent infections caused by human papillomavirus (HPV) is a key aetiological factor in the development of cervical lesions and cervical cancer [ 3].
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Infection with the human papillomavirus is an important co-factor in the development of cervical carcinomas.
Epidemiological studies have demonstrated the importance of host genetic susceptibility factors in the development of cervical cancer.
We have investigated the potential role of oxidation products of the polyamines spermine and spermidine and the diamine putrescine in seminal plasma (SP) as co-factors in the development of cervical cancer.
DOI: 10.1038/sj/bjc/6600024 www.bjcancer.com © 2002 The Cancer Research Campaign High-risk human papillomaviruses (HPVs), especially of type 16, are considered to be the most important risk factors in the development of cervical neoplasias (zur Hausen, 1991; Walboomers et al, 1999).
To evaluate the risk factors potentially involved in the development of cervical intraepithelial neoplasia (CIN) recurrence after cervical conization in a long-term follow-up period.
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