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N-cadherin is considered to be the key factor in directing cell cell interactions during mesenchymal condensation, which is essential to osteogenesis.
In conclusion, our data show that regulation of ANGPTL4 is an important factor in directing lipid fuels towards BAT and away from WAT during prolonged cold exposure.
These data further support that H3K27me3 is a major factor in directing aberrant DNA methylation during malignant progression, but the phenotypic effects of this phenomenon are unknown since it has not been associated with gene expression changes.
It is essential when unraveling the role of a transcription factor in directing organogenesis to take the complementary and supporting roles played by other transcription factors that are active in the same cells into consideration.
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mRNA localization, for ß-actin in particular, has been previous implicated as a factor in directed cell migration46.
The functional involvement of these genes and factors in directing organ-specific metastasis was demonstrated subsequently.
However, there was scant information regarding the role, if any, of core promoter factors in directing the network of gene transcription necessary to form neurons.
Synthetic biology can also be applied to identify and understand the controlling factors in directing carbon flux to the FA pathway (Liu and Khosla, 2010).
Analysis of gene expression comparing 4T1 and two of its non-metastatic sibling cell lines suggested prominent roles for several signaling pathways and secreted factors in directing microenvironmental changes within the tumor leading to tumor cell dissemination and metastasis.
The GATA motif (WGATAR) is the major sequence determinant of GATA1 binding, and it is also the TF binding site motif most strongly associated with TAL1 occupancy, reflecting a strong role of GATA factors in directing the binding of TAL1 [ 37, 72].
IGF2 encodes an endocrine and autocrine/paracrine-acting factor important in directing growth during prenatal development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com