Although anemia itself has been considered to be a risk factor for a complication in the past, it more accurately represents only a predictor of receiving an erythrocyte transfusion.
In the ICHD-III classification[2] we find a group of MA complications as persistent aura without infarction and migrainous infarction; we performed a literature research to find if there were other possible modifications in typical aura presentation that could represent a risk factor of a complication as in the case here reported.
Oxidative stress has been suggested to be a contributory factor in development and complication of diabetes [1 3].
Chronic formation and accumulation of AGEs has been demonstrated to be an important factor in diabetic complications, 12 while increased sRAGE levels have a protective effect for diabetic conditions, including macrovascular complications.
Increased activity of the polyol pathway is an important pathogenic factor in diabetic complications [ 3,8,17] and several inhibitors of aldose reductase, a key enzyme in this pathway, have been developed.
However, even though fluid restriction seems to be an important factor in reducing complications after pneumonectomy, it may compromise cardiac output and ultimately lead to inadequate oxygen delivery.
However, while hyperglycemia is an important factor in microvascular complications of diabetes, its role in macrovascular events is less dominant [ 4] and animal studies have not been consistent [ 5- 8].
This type of carbonyl stress was first identified in diabetes and is regarded as the most important factor in diabetic complications [ 13].
The disease is not only a major factor in the cardiovascular complications of diabetes mellitus (DM) [ 1], but it also affects many other major segments of the general population, such as the elderly and patients with hypertension (PH), metabolic syndrome (MetS), and connective tissue disorders [ 2- 4].
Furthermore, we analysed factors that could possibly be related to these cases of ΔVAS ≥ 3 and factors related to cases in which a complication occurred.
Additionally, intravascular volume may be the most important factor in complications associated with dehydration such as hypo-volemic shock or acute kidney injury.
