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Yagnik, D. Macrophage derived platelet activating factor implicated in the resolution phase of gouty inflammation.
Oxidative protein damage is the most critical factor implicated in carcinogenesis and other disorders.
Oxidative stress is a major factor implicated in the degeneration of cholinergic neurons in Alzheimer's disease.
SIRT3 has also been shown to interact with FoxO3a, the transcription factor implicated in ROS regulation and to activate FoxO3a-dependent gene expression46,47.
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor implicated in the regulation of apoptosis and proliferation.
Hypoxia of renal medulla is a key factor implicated in the development of drug-induced renal failure.
Magnesium deficiency has recently been proposed as a novel factor implicated in the pathogenesis of diabetes complications.
Among adolescents, anhedonia the reduced ability to experience pleasure or reduced reactivity to pleasurable cues is a transdiagnostic risk factor implicated in psychiatric illness, treatment non-response, and suicidal behaviors.
Soluble endoglin is an anti-angiogenic factor implicated in the pathogenesis of the disease, however little is known about its molecular regulation.
Progranulin (PGRN) is a growth factor implicated in various pathophysiological processes, including wound healing, inflammation, tumorigenesis, and neurodegeneration.
Inhibition of growth at the distal tibial physis appears to be the primary factor implicated in the shortening [4] and thus causes shortening throughout growth.
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