Exact(24)
In the multi-variate analysis, a KRAS mutation was a poor prognostic factor (hazard ratio = 2.6, 95 % CI 1.8 3.7).
In multivariate survival analyses, fibrinogen was found to be an independent prognostic factor (hazard ratio 1.81, CI 1.23 2.65).
Multivariate analysis revealed that downregulation of PML was an independent unfavorable prognostic factor (hazard ratio = 2.739; P = 0.001).
For each prognostic factor, hazard ratio (HR) for DFS and 95 % CI was calculated using the simple Cox model.
For the entire follow-up period, diabetes was a significant prognostic factor, hazard ratio 1.47 (CI 1.35-1.61) adjusted for all covariates.
The backward elimination procedure retained CT-response as a prognostic factor (hazard ratio 0.59 (0.39–0.91) for responding patients, p = 0.017, chi test).
Similar(36)
A Cox proportional hazards model indicated that negative EGFR mutation was a secondary prognostic factor (hazards ratio: 2.259, P=0.036).
The association of GM with 1-year TVR was independent of clinical or anatomic factors (hazard ratio 2.0, 95% confidence interval 1.0 to 4.02, p = 0.05).
This association was significant after adjusting for several risk factors (hazard ratio 3.01; 95% C.I = 1.19 7.60; P = 0.020).
For further work, the risk-factor hazard function, the impact of which on survival varies over time, should be evaluated.
However, the prognosis of patients at the same stage is not completely homogeneous, and the risk-factor hazard function is not constant over time.
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