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Smokers have a greater risk factor in the pathogenesis and progression of periodontal disease.
Inflammation is an important factor in the pathogenesis and progression of heart failure.
Cigarette smoking is a significant risk factor in the pathogenesis and progression of periodontal disease [ 1, 2].
Simultaneous exposure of people to heavy metals and nephrotoxic pesticides may be a contributory factor in the pathogenesis and progression of CKDu.
Increased oxidative stress and impaired antioxidant defense mechanisms are important factors in the pathogenesis and progression of diabetes mellitus and other oxidant-related diseases.
There is a growing awareness of the importance of biomechanical factors in the pathogenesis and progression of knee osteoarthritis [ 4- 6].
Almost all of the proinflammatory factors involved in the pathogenesis and progression of OA and RA are regulated by the transcription factor NF-κB [ 20].
The pathophysiological mechanisms of DN are incompletely understood, but numerous factors contribute to the pathogenesis and progression of DN.
Many factors are involved in the pathogenesis and progression of BC, including genetic, biological, and environmental factors, as well as lifestyle [ 6].
However, considerable evidence indicates that psychosocial factors are involved in the pathogenesis and progression of cardiovascular disease (CVD).
Vascular diseases as well as vascular risk factors are involved in the pathogenesis and progression of Alzheimer's dementia [ 45, 46].
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