Sentence examples for fact mediated from inspiring English sources

We found that the anti-apoptotic effect of 17β-estradiol in HCC38 breast cancer cells is in fact mediated by membrane-associated ERα36.

As heated serum alone had no major influence on transgene delivery, we concluded that the effect had been in fact mediated by the growth medium used as diluent.

This suggests that the escape response associated with the acj6 phenotype is in fact mediated by acj6-expressing neurons, whose activity is necessary and sufficient for this behavior.

It is therefore possible that many of the diverse functions of exosomes reported in different studies are in fact mediated by different RNA signals that are shuttled between cells by exosomes.

However, for eukaryotic systems, it is speculated that the total number of protein phosphatase holoenzymes might even exceed the protein kinase repertoire because the specificity of many of these enzymes is in fact mediated by accessory proteins [56], [57].

In the current studies, we sought to better connect PGE2-induced PKA activity with downstream effects on AMPA receptors by determining whether PGE2 leads to increased phosphorylation of GluR1 and AMPA receptor trafficking to the membrane, and whether these effects of PGE2 on GluR1 are in fact mediated by PKA.

In an interview, Chenjerai Hunzvi, the leader of the militants' Zimbabwe National Liberation War Veterans Association, denied that his organization was behind any of the reported violence and said the militants were in fact mediating disputes between companies and their employees to avert violence.

Direct evidence that anti-Hebbian synaptic plasticity does in fact mediate the selection process has come from work in retina [13] and in cerebellum-like structures [12], [26].

Our observations together with the published importance of the P-loop in mammalian EHDs leads us to the possibility that the P-loop is required for proper membranal localization of AtEHD2, while the coiled-coil in fact mediates the binding to "target" proteins thereby enabling the inhibitory function on endocytosis.

Thus, homework compliance may in fact mediate the association between patients' outcome expectations and treatment outcomes.

Whether adiponectin is simply a marker for PPAR-γ signaling or, in fact, mediates its anti-fibrotic activities is currently unknown.