Sentence examples for facing severe disadvantages from inspiring English sources

Since clinically used compounds such as Paclitaxel or Vincristine are facing severe disadvantages, namely a small therapeutic window, restrictions in bioavailability and solubility, a complex synthesis and most importantly development of drug resistance in patients, special emphasis is laid on the development of synthetic small molecule tubulin inhibitors (SMTIs).

But in more momentous ways, the president was facing serious disadvantages, some of his own making.

We fund and support innovative practice, policy and research to understand how change happens for people facing severe and multiple disadvantage.

Iran is facing severe drought conditions.

Therefore, chip security is facing severe threats.

Currently Pakistan is facing severe energy crisis and power failures.

By targeting people who face severe and multiple disadvantages, the foundation aims to support "systems change" – which is defined in a 2015 publication from New Philanthropy Capital as "altering underlying structures and supporting mechanisms which make the system operate in a particular way".

Our vision is of a society where everyone can lead a rewarding life and people who face severe and multiple disadvantage such as homelessness, substance misuse, mental illness, violence and abuse and chronic poverty are able to participate fully with healthy networks of support.

Industry faces severe power restrictions.

Mergers face severe antitrust hurdles.

Some 1.5m will face "severe food insecurity".