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These complexes would provide a cytoskeletal platform that regulates the accurate clustering and activation of β2-integrins [4], facilitating their function [34].
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They reduce peroxiredoxins and peroxidases, facilitating their functions, and act as hydroxyl radical scavengers [63].
Histone proteins can be modified on the N-terminal tail and the modifications can disrupt the interaction between nucleosomes to prevent the packaging of chromatin into higher order structures; also the modified tails can serve as binding sites for chromatin modifiers, facilitating their functions [ 1].
PACAP deficiency decreases early accumulation of neutrophils by slowing their extravasation from the vessels, but facilitates their function in the later phase.
Integrin-dependent activation of L-type VDCCs has also been shown to be dependent on PKA [ 47], which phosphorylates VDCCs and facilitates their function [ 97].
Thus, we predict a rapid growth in studies using neurostimulation to understand the role of specific frequencies of oscillations for specific cognitive processes and for entrainment to facilitate their function.
These data suggest that Chordin locally antagonizes BMP signaling by binding NvDpp and NvBMP5-8, but facilitates their function at a distance acting as a shuttle molecule, similar to the situation in Drosophila (Eldar et al., 2002) and Xenopus (Ben-Zvi et al., 2008).
Ca2+ signalling would appear to be mediated through Ca2+-dependent protein kinases during uniform wall formation while a calmodulin signalling route could operate when wall ingrowths are being deposited as suggested by expression of three IQ-domain containing proteins (Additional file 11) that bind calmodulins to facilitate their function.
Because they can bind groups of protein partners and facilitate their functions, they have been referred to as "molecular facilitators", "molecular organizers", "tetraspanin networks", and "membrane microdomains" [ 84, 85].
Cells usually facilitate their functions under various fluctuated environments.
Although it is not easy to directly control the extracellular noise intensity for achieving the most pronounced synchronized switching, we expect that biological systems possibly use some regulatory mechanisms to optimally facilitate their functions during internal cellular processes.
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